Director, US Center for Outcomes Research, Real-World Evidence and Epidemiology (CORE)

At Genmab, we are dedicated to building extra[not]ordinary® futures, together, by developing antibody products and groundbreaking, knock-your-socks-off KYSO antibody medicines® that change lives and the future of cancer treatment and serious diseases. We strive to create, champion and maintain a global workplace where individuals’ unique contributions are valued and drive innovative solutions to meet the needs of our patients, care partners, families and employees.

Our people are compassionate, candid, and purposeful, and our business is innovative and rooted in science. We believe that being proudly authentic and determined to be our best is essential to fulfilling our purpose. Yes, our work is incredibly serious and impactful, but we have big ambitions, bring a ton of care to pursuing them, and have a lot of fun while doing so.

Does this inspire you and feel like a fit? Then we would love to have you join us!

The Role

The Director, US CORE leads the US-focused CORE strategy for a defined therapeutic area. This role partners closely with US Medical Affairs, US Market Access, Commercial, Global CORE, and RWE Analytics to generate and translate high-quality evidence that supports product value, payer decision-making, and patient access in the US healthcare environment.

The role works in close collaboration with the US Field Health Evidence Outcomes Liaison (HEOL) team to ensure field readiness, understand access barriers and customer insights, and inform evidence-generation strategies that address US payer and population health decision maker (PHDM) needs.

Work arrangement: This role offers flexibility to work away from the office for 20%–40% of a typical schedule. Employees may use this work schedule in increments of single days or multiple consecutive days, provided it does not exceed 40% within a 60-day period, and is approved by the hiring manager.

Responsibilities

Strategy & Leadership

• Lead the development of the US CORE strategy and tactical plan aligned with US brand, medical, and market access priorities.

• Partner with Global CORE and external vendors to execute priority CORE studies for the US market, providing strategic oversight to ensure scientific rigor, relevance, compliance, and alignment on study design, timing, impact, and dissemination.

• Leverage RWE to identify data-driven insights on unmet needs and disease burden that inform and strengthen therapeutic area positioning

• Represent US CORE on key cross-functional and global teams, contributing to evidence gap assessments, launch readiness/brand planning and integrated evidence planning.

• Inform Global CORE strategy by providing US market insights and support evidence needs for US pipeline assets as appropriate.

• Lead or actively participate in US payer or RWE advisory boards, as appropriate, to gather insights on key evidence needs and inform CORE data generation plans

• Develop and maintain understanding of US payer, IDN, and population health evidence needs to inform evidence generation.

• Evaluate US real-world data sources to inform evidence-generation strategy across the portfolio.

• Foster relationships with US Key Opinion Leaders (KOLs) to collect clinical insights on CORE research

Value Communication

• Lead the development of US payer- and PHDM-focused CORE value communication tools (e.g., field decks, BIMs, cost calculators, FAQs, Section 4 AMCP Dossier).

• Partner with external vendors to develop customer-centric evidence packages and serve as CORE lead for internal medical, regulatory, and legal review processes.

• Collaborate with Market Access Marketing to co-develop shared Market Access and HEOL resources, ensuring scientific rigor, appropriate use of CORE publications, and clear interpretation of findings.

• Lead the development of internal, evidence-based value narrative for Genmab products

• In partnership with Medical Information, provide CORE scientific leadership for submissions to NCCN, clinical pathway organizations, and formulary decision making committees

• Contribute to scientific publications and presentations for CORE studies relevant to the US market, including peer-reviewed journals and medical congresses.

• Maintain awareness of competitor HEOR and RWE data and communicate key insights to internal stakeholders and appropriate US field-facing teams.

Pull-Through of Value Communication & Payer-Focused Engagements

• Partner closely with the US HEOL team to ensure field readiness and effective pull-through of CORE field resources and publications

• Provide input into customer engagement plan to understand challenges and align to key resources

• Engage with US customers and Key Opinion Leaders (KOLs) to support site-facing research and collect clinical insights on key research studies.

• Support scientific training and enablement of HEOLs and other US field-facing teams to ensure confident, compliant payer engagement.

• Develop Key Insight Topics (KITs) and Key Insight Questions (KIQs) to support HEOL customer engagements and structured collection of payer and PHDM insights.

• Translate HEOL field insights on evidence needs and access barriers into actionable CORE research strategies and tactic

• Participate in access decision maker engagements as needed

Qualifications

• Advanced degree required (PhD, PharmD, MD, or Master’s with significant relevant experience) in HEOR, epidemiology, public health, health services research, health policy, or a related discipline.

• 8–10+ years of experience in the biopharmaceutical or life sciences industry with strong HEOR/RWE and US market access experience.

• Oncology experience strongly preferred.

• Demonstrated scientific contributions, including peer-reviewed publications and/or scientific congress presentations.

• Strong understanding of the US healthcare, payer, and reimbursement landscape.

• Excellent communication skills with proven ability to lead and influence in a cross-functional, matrixed environment.

For US based candidates, the proposed salary band for this position is as follows:

The actual salary offer will carefully consider a wide range of factors, including your skills, qualifications, experience, and location. Also, certain positions are eligible for additional forms of compensation, such as discretionary bonuses and long-term incentives. 

When you join Genmab, you’re joining a culture that supports your physical, financial, social, and emotional wellness. Within the first year, regular full-time U.S. employees are eligible for:

• 401(k) Plan: 100% match on the first 6% of contributions

• Health Benefits: Two medical plan options (including HDHP with HSA), dental, and vision insurance

• Voluntary Plans: Critical illness, accident, and hospital indemnity insurance

• Time Off: Paid vacation, sick leave, holidays, and 12 weeks of discretionary paid parental leave

• Support Resources: Access to child and adult backup care, family support programs, financial wellness tools, and emotional well-being support

• Additional Perks: Commuter benefits, tuition reimbursement, and a Lifestyle Spending Account for wellness and personal expenses 

About You

• You are genuinely passionate about our purpose

• You bring precision and excellence to all that you do

• You believe in our rooted-in-science approach to problem-solving

• You are a generous collaborator who can work in teams with a broad spectrum of backgrounds

• You take pride in enabling the best work of others on the team

• You can grapple with the unknown and be innovative

• You have experience working in a fast-growing, dynamic company (or a strong desire to)

• You work hard and are not afraid to have a little fun while you do so!

Locations

Genmab maximizes the efficiency of an agile working environment, when possible, for the betterment of employee work-life balance. Our offices are crafted as open, community-based spaces that work to connect employees while being immersed in our powerful laboratories. Whether you’re in one of our office spaces or working remotely, we thrive on connecting with each other to innovate.

About Genmab

Genmab is an international biotechnology company with a core purpose to improve the lives of patients through innovative and differentiated antibody therapeutics. For 25 years, its hard-working, innovative and collaborative team has invented next-generation antibody technology platforms and harnessed translational, quantitative and data sciences, resulting in a proprietary pipeline including bispecific T-cell engagers, antibody-drug conjugates, next-generation immune checkpoint modulators and effector function-enhanced antibodies. By 2030, Genmab’s vision is to transform the lives of people with cancer and other serious diseases with Knock-Your-Socks-Off (KYSO®) antibody medicines.

Established in 1999, Genmab is headquartered in Copenhagen, Denmark with international presence across North America, Europe and Asia Pacific. For more information, please visit Genmab.com and follow us on LinkedIn and X.

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Please note that if you are applying for a position in the Netherlands, Genmab’s policy for all permanently budgeted hires in NL is initially to offer a fixed-term employment contract for a year, if the employee performs well and if the business conditions do not change, renewal for an indefinite term may be considered after the fixed-term employment contract.